Written by Jessie, Product Manager · Updated 6 November 2026
Does Herbal Harmony: Meno Rebalance have side effects?
Herbal Harmony: Meno Rebalance has 514 mg of EstroG-100®, a Korean herbal blend that eased hot flushes, sleep trouble and other menopause symptoms in placebo-controlled trials, with no adverse events reported over 12 weeks. Lab tests detected none of 19 hormones. It isn't advised in pregnancy or breastfeeding. If you take HRT or medication, check with your doctor first.
This article is for you if: you're in perimenopause or menopause, you're thinking about Herbal Harmony: Meno Rebalance, and you want to know exactly what's inside, what the research and our lab tests show, and whether it suits you.
If hot flushes, night sweats and broken sleep have you looking at Herbal Harmony: Meno Rebalance, it makes sense to check what's in it before you start. Here we cover every key ingredient and its amount, what trials of its herbal blend found, our published lab results, who should speak to a doctor first, and how to take it.
→ See Herbal Harmony: Meno Rebalance, our daily herbal scoop for perimenopause and menopause
In this article
- What's inside Herbal Harmony: Meno Rebalance?
- What do trials show for menopause symptoms?
- What do studies say about side effects?
- Does Herbal Harmony: Meno Rebalance contain hormones?
- Who is it for, and who should check with a doctor first?
- How do you take it, and how long before you notice a difference?
- Frequently asked questions
What's inside Herbal Harmony: Meno Rebalance?
Each 13 g scoop gives you 514 mg of EstroG-100®, a patented extract of three Korean herbs, plus carob bean extract, iron and black pepper extract, in a powder that tastes of longan and red dates. Every key ingredient is listed with its amount.
| Ingredient | Per 13 g scoop | What it is |
|---|---|---|
| EstroG-100® | 514 mg | A patented extract of Cynanchum wilfordii, Phlomis umbrosa and Angelica gigas, three herbs with a long history of use in Korea. It is the headline ingredient, at the same daily amount used in the main trial.[1] |
| Carob bean extract | 50 mg | A natural source of D-chiro-inositol |
| Microencapsulated iron (Lipofer®) | 12 mg | Iron, an essential mineral, in a microencapsulated form |
| Rephyll® black pepper extract | 100 mg | A black pepper extract, added to help the herbs absorb |
| Isomalto-oligosaccharide (IMO) | Main ingredient | A prebiotic fibre that forms the base of the powder |
| Longan and red dates juice powder | For flavour | Gives the drink its longan and red date taste |
Sources: our product guide, product page and product information sheet, checked 6 November 2026.
A few notes for diets and allergies:
- Sugar: about 1 g per scoop. Our lab test measured 7.9 g of sugar per 100 g of powder.[3]
- Caffeine: none of the ingredients contain caffeine, so it suits a scoop before bed.
- Halal: certified by JAKIM, the Department of Islamic Development Malaysia.
- Vegan: vegan-friendly, with no animal-derived ingredients.[5]
- Free from: gluten and dairy, with no preservatives and no artificial colouring.
- Allergens: made on equipment that also processes gluten, fish, milk, soy, nuts, sesame seed and sulphur dioxide.
- Format: a 390 g tub with 30 scoops, a full month, or a box of 30 single-serve sachets.
What do trials show for menopause symptoms?
In placebo-controlled trials, women taking EstroG-100® reported clear relief from hot flushes and a wide range of other menopause symptoms, starting within the first 6 weeks.
- A 12-week trial of 64 women in the US, before, during and after menopause. Women took 514 mg of EstroG-100® a day, the same amount as one scoop of Herbal Harmony: Meno Rebalance, or a placebo. Their average score on the Kupperman menopause index, which rates 11 common symptoms, fell from 29.5 to 13.6 by week 6 and to 11.3 by week 12, a drop of about 62%. On placebo it fell by about 19%, from 29.2 to 23.7. Hot flushes and night sweats, trouble sleeping, nervousness, low mood, dizziness, tiredness, joint and muscle aches, tingling and vaginal dryness all improved significantly more than with placebo.[1]
- A 12-week trial in postmenopausal women with hot flushes, in Iran. Women took EstroG-100® or a placebo every day. By week 6, the EstroG-100® group reported fewer mild, moderate and severe hot flushes than the placebo group, and the researchers concluded that the extract could improve hot flushes in postmenopausal women.[2]
Herbal Harmony: Meno Rebalance works best as daily support alongside the habits that help most, such as a cool bedroom, regular movement and knowing your triggers. Read more about what actually helps hot flushes and night sweats in perimenopause, and how herbal options fit a wider plan in our guide to phytoestrogens and herbal support in perimenopause.
What do studies say about side effects?
In the 12-week trial, no adverse events were observed or reported by the women taking EstroG-100®.[1] The researchers also checked the things people often worry about with menopause support:
- Weight: women taking EstroG-100® did not gain weight.
- Hormone levels: oestradiol, the main form of oestrogen, and FSH, the hormone that rises around menopause, did not change significantly in the EstroG-100® group.
- Liver and blood fats: liver enzymes stayed steady, and total cholesterol, LDL, HDL and triglycerides showed no significant change.
Our label adds the same simple advice we give for every product: stop taking it if you're unwell or have an allergic reaction.
Does Herbal Harmony: Meno Rebalance contain hormones?
No. There are no hormones in the formula, and an independent laboratory in Malaysia screened it for 19 natural and synthetic hormones, including oestradiol, oestrone, progesterone and testosterone, with none detected.[3] Its published reports show:
- Hormones: none of the 19 hormones tested was detected.
- Heavy metals: arsenic, lead, mercury, cadmium and antimony were not detected.
- Microbes: no yeast, mould, coliforms, E. coli or Staphylococcus aureus were detected, and salmonella was absent.
- Sachets: the single-serve sachets have their own heavy metal and microbe reports.
This matters because in Singapore, health supplements are not approved or licensed by the Health Sciences Authority (HSA) before they're sold. HSA prohibits medicinal ingredients such as steroids in supplements and sets strict limits on toxic heavy metals, and the seller must make sure the product is not harmful.[4] Our guide on how to read a supplement label in Singapore explains what else to look for. Herbal Harmony: Meno Rebalance is prepared in an FDA-registered, GMP-certified facility in Malaysia, our production partners hold FDA, HACCP and ISO 22000 certifications, and we run extra testing in Taiwan and Singapore to screen for commonly found medicines.[5] You can open every report on our lab tests page.
Who is it for, and who should check with a doctor first?
Herbal Harmony: Meno Rebalance is made for women in perimenopause and menopause who want daily herbal support for hot flushes, night sweats, broken sleep, low mood and joint aches, with no hormones in the formula. The main EstroG-100® trial included women before, during and after menopause.[1]
Check with your doctor before you start if any of these apply to you:
- Pregnancy and breastfeeding. Our label advises that pregnant or breastfeeding women should not take Herbal Harmony: Meno Rebalance.
- Hormone replacement therapy (HRT) or other hormonal treatment. If you take HRT or any hormonal treatment, talk to your healthcare provider before you add Herbal Harmony: Meno Rebalance.
- A history of hormone-sensitive cancer. The main EstroG-100® trial did not include women with a history of breast cancer or other hormone-dependent cancer, or those who had used oestrogen or progestin products in the previous 3 months, so ask your doctor first.[1]
- Medication or a medical condition. Our label asks you to consult a doctor if you take any medication or have a medical condition.
- Allergies. Read the full ingredient list and the shared-equipment note above.
How do you take it, and how long before you notice a difference?
Take one scoop a day, every day, and give it at least a month before you judge it. Our product guide has how to take and store every product.
- How much: 1 scoop (13 g) a day, or 1 sachet if you have the box.
- How: mix with 300 to 350 ml of water and stir well.
- When: before breakfast or before bed. Many customers like it in the evening.
- How long: results are best seen after 1 month of daily use, and for best results we recommend at least 3 months of consistent daily use. That matches the main trial, where symptom scores had dropped by week 6 and kept improving to week 12.[1]
- With other products: our products can be taken together every day, as long as you follow each one's directions, and Herbal Harmony: Meno Rebalance can sit alongside your other supplements. If you take medication or have a health condition, check with your doctor.[5]
Herbal Harmony: Meno Rebalance gives you 514 mg of EstroG-100® in every scoop, with carob bean extract and 12 mg of iron, in a longan and red date drink with about 1 g of sugar. It's halal-certified, vegan-friendly and free from gluten and dairy, and its lab reports, including the 19-hormone screen, are published for you to check.
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Related reading: Why sleep falls apart in perimenopause, and what may help · Phytoestrogens and herbal support in perimenopause · How to read a supplement label in Singapore
Frequently asked questions
What do reviews of Herbal Harmony: Meno Rebalance say?
You can read hundreds of customer reviews on our product page, and most of them give Herbal Harmony: Meno Rebalance 4 or 5 stars. Results vary from person to person, so take it daily for at least a month before you judge it.
Is Herbal Harmony: Meno Rebalance halal?
Yes. Herbal Harmony: Meno Rebalance is halal-certified by JAKIM, the Department of Islamic Development Malaysia. It is also vegan-friendly, and like all our products, it is free from porcine-derived ingredients.
Is Herbal Harmony: Meno Rebalance approved by HSA?
HSA does not approve or license health supplements before they are sold in Singapore, so no supplement can truly be called HSA approved. Sellers are responsible for making sure their products are safe, and HSA prohibits medicinal ingredients such as steroids in supplements. We publish the lab reports for Herbal Harmony: Meno Rebalance, including its hormone screen, so you can check them yourself.
Can I take Herbal Harmony: Meno Rebalance every day?
Yes. Herbal Harmony: Meno Rebalance is made to be taken once a day. In the 12-week trial of EstroG-100®, no adverse events were reported, there was no weight gain, and liver enzymes and oestrogen levels stayed steady. If you have a specific health concern or take medication, check in with your doctor along the way.
What's the difference between Herbal Harmony: Meno Rebalance and Hormone Harmony?
Herbal Harmony: Meno Rebalance is made for perimenopause and menopause, with 514 mg of EstroG-100® per scoop. Hormone Harmony is made for cycle support, with 2,000 mg of myo-inositol, 50 mg of D-chiro-inositol and 257 mg of a blend of the same three Korean herbs. Both are halal-certified by JAKIM, so choose the one that matches your life stage.
Key takeaways
- Each scoop of Herbal Harmony: Meno Rebalance has 514 mg of EstroG-100®, 50 mg of carob bean extract, 12 mg of iron and 100 mg of black pepper extract, with about 1 g of sugar and no caffeine-containing ingredients.
- In a 12-week placebo-controlled trial, 514 mg of EstroG-100® a day cut average menopause symptom scores by about 62%, and a second trial found fewer hot flushes by week 6.
- No adverse events were reported in the 12-week trial, there was no weight gain, and liver enzymes and oestrogen levels stayed steady.
- An independent lab detected none of the 19 hormones it tested for, and none of the heavy metals or harmful microbes it screened for.
- It isn't advised in pregnancy or breastfeeding. Check with your doctor first if you take HRT or other medication, have a medical condition or have had a hormone-sensitive cancer.
- Take 1 scoop a day before breakfast or bed, for at least a month, ideally 3 months.
About the author: Jessie is the Product Manager at The Purest Co. A Biomedical Science graduate from the International Medical University Malaysia, she has over five years in the nutraceutical industry, sourcing high-quality herbs to create supplements that are enjoyable and effective. She keeps up with new research through global conferences.
References
[1] Chang A, Kwak BY, Yi K, Kim JS. The effect of herbal extract (EstroG-100) on pre-, peri- and post-menopausal women: a randomized double-blind, placebo-controlled study. Phytother Res. 2012.
[2] Farzaneh F, Fallah G, Khalili-Chelik A, Fallah A, Hosseini M. Estro G-100 herbal extract and hot flashes in postmenopausal women: a randomized double-blinded controlled trial. Explore (NY). 2024.
[3] The Purest Co. Lab tests: published reports for Herbal Harmony: Meno Rebalance, including the hormone screen, heavy metals, microbes and sugar content.
[4] Health Sciences Authority. Health supplements: overview. Last updated 30 October 2026.
[5] The Purest Co. Help Center: certified manufacturing, extra testing, vegan-friendly products and taking our products together.
These statements have not been evaluated by any regulatory authority. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Consult a healthcare provider before use if you are pregnant, breastfeeding, or on prescribed medication.